Category Archives: Eur J Heart Fail

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Quality of life and survival in patients with heart failure.
Eur J Heart Fail. 2013 Jan;15(1):94-102
Authors: Hoekstra T, Jaarsma T, van Veldhuisen DJ, Hillege HL, Sanderman R, Lesman-Leegte I
Abstract… Continue reading →

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Caregiver burden in partners of Heart Failure patients; limited influence of disease severity.
Eur J Heart Fail. 2007 Jun-Jul;9(6-7):695-701
Authors: Luttik ML, Jaarsma T, Veeger N, Tijssen J, Sanderman R, van… Continue reading →

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Depressive symptoms and outcomes in patients with heart failure: data from the COACH study.
Eur J Heart Fail. 2009 Dec;11(12):1202-7
Authors: Lesman-Leegte I, van Veldhuisen DJ, Hillege HL, Moser D, Sanderman … Continue reading →

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Quality of life is impaired similarly in heart failure patients with preserved and reduced ejection fraction.

Eur J Heart Fail. 2011 Sep;13(9):1013-8

Authors: Hoekstra T, Lesman-Leegte I, van Veldhuisen DJ, Sanderman R, Jaarsma T

Abstract
AIMS: To compare quality of life (QoL) in heart failure (HF) patients with preserved ejection fraction (HF-PEF) and HF patients with reduced ejection fraction (HF-REF) in a well-defined HF population.
METHODS AND RESULTS: Patients with HF-PEF [left ventricular ejection fraction (LVEF) ≥40%] were matched by age and gender to patients with HF-REF (LVEF <40%). In the current study, we only included HF patients with a B-type natriuretic peptide level (BNP) >100 pg/mL. Quality of life was assessed by Cantril’s Ladder of Life, RAND-36, and the Minnesota Living with Heart Failure questionnaire, and impairment of QoL was adjusted for by BNP as a marker for severity of HF. We examined a total of 290 HF patients, of whom 145 had HF-PEF (41% female; age 72 ± 10; LVEF 51 ± 8%) and 145 had HF-REF (41% female; age 73 ± 10, LVEF 26 ± 7%). All HF patients reported markedly low scores of QoL, both on the general and disease-specific QoL questionnaires. Quality of life between patients with HF-PEF and HF-REF did not differ significantly. When adjusting the QoL scores for BNP, an association between QoL and LVEF was not found, i.e. patients with HF-PEF and HF-REF with similar BNP levels had the same impairment in QoL.
CONCLUSION: Quality of life is similarly impaired in patients with HF-PEF as in HF-REF. These findings further support the need for more pharmacological and non-pharmacological studies in patients with HF-PEF. Trial registration number: NCT 98675639.

PMID: 21712287 [PubMed – indexed for MEDLINE]

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Depressive symptoms are prominent among elderly hospitalised heart failure patients.
Eur J Heart Fail. 2006 Oct;8(6):634-40
Authors: Lesman-Leegte I, Jaarsma T, Sanderman R, Linssen G, van Veldhuisen DJ
… Continue reading →