Monthly Archives: May 2016

Impaired Mood in Headache Clinic Patients: Associations With the Perceived Hindrance and Attainability of Personal Goals






CONCLUSION: The results of this preliminary study suggest that perceptions of increased goal hindrance and decreased goal attainability may indeed be a risk factor for impaired mood in the headache clinic population and highlight the need for further, longitudinal research. Obtaining more insight into goal processes (eg, what types of goals are specifically disturbed, which goal adjustment strategies are (mal)adaptive) may help to identify ways to improve outcomes in the headache clinic… Continue reading

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Co-morbidity of depression, anxiety and fatigue in cancer patients receiving psychological care






CONCLUSIONS: Three distinct co-morbidity patterns of depression, anxiety and fatigue were identified and exhibited different symptom courses longitudinally. Those with poor physical health tended to report elevated mood disturbances and fatigue during psychological care. Copyright © 2016 John Wiley & Sons, Ltd. Continue reading

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Route complexity and simulated physical ageing negatively influence wayfinding






The aim of this age-simulation field experiment was to assess the influence of route complexity and physical ageing on wayfinding. Seventy-five people (aged 18-28) performed a total of 108 wayfinding tasks (i.e., 42 participants performed two wayfinding tasks and 33 performed one wayfinding task), of which 59 tasks were performed wearing gerontologic ageing suits. Outcome variables were wayfinding performance (i.e., efficiency and walking speed) and physiological outcomes (i.e., heart and… Continue reading

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Interventions based on self-management of well-being theory: pooling data to demonstrate mediation and ceiling effects, and to compare formats.






Interventions based on self-management of well-being theory: pooling data to demonstrate mediation and ceiling effects, and to compare formats.
Aging Ment Health. 2016 May 12;:1-7
Authors: Goedendorp MM, Steverink N
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Population-based preconception carrier screening: how potential users from the general population view a test for 50 serious diseases.






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Population-based preconception carrier screening: how potential users from the general population view a test for 50 serious diseases.
Eur J Hum Genet. 2016 May 11;
Authors: Plantinga M, Birnie E, Abb… Continue reading

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Interventions based on self-management of well-being theory: pooling data to demonstrate mediation and ceiling effects, and to compare formats






CONCLUSION: Support for SMW theory was found, i.e. increasing self-management ability lead to improved well-being. Some ceiling effect was found. We conclude that various SMW interventions formats can improve self-management abilities and well-being with medium effects. Continue reading

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Population-based preconception carrier screening: how potential users from the general population view a test for 50 serious diseases






With the increased international focus on personalized health care and preventive medicine, next-generation sequencing (NGS) has substantially expanded the options for carrier screening of serious, recessively inherited diseases. NGS screening tests not only offer reproductive options not previously available to couples, but they may also ultimately reduce the number of children born with devastating disorders. To date, preconception carrier screening (PCS) has largely targeted single diseases… Continue reading

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Malnutrition is associated with worse health-related quality of life in children with cancer.






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Malnutrition is associated with worse health-related quality of life in children with cancer.

Support Care Cancer. 2015 Oct;23(10):3043-52

Authors: Brinksma A, Sanderman R, Roodbol PF, Sulkers E, Burgerhof JG, de Bont ES, Tissing WJ

Abstract
PURPOSE: Malnutrition in childhood cancer patients has been associated with lower health-related quality of life (HRQOL). However, this association has never actually been tested. Therefore, we aimed to determine the association between nutritional status and HRQOL in children with cancer.
METHODS: In 104 children, aged 2-18 years and diagnosed with hematological, solid, or brain malignancies, nutritional status and HRQOL were assessed at diagnosis and at 3, 6, and 12 months using the child- and parent-report versions of the PedsQL 4.0 Generic scale and the PedsQL 3.0 Cancer Module. Scores on both scales range from 0 to 100.
RESULTS: Undernourished children (body mass index (BMI) or fat-free mass < -2 standard deviation score (SDS)) reported significantly lower PedsQL scores compared with well-nourished children on the domains physical functioning (-13.3), social functioning (-7.0), cancer summary scale (-5.9), and nausea (-14.7). Overnourished children (BMI or fat mass >2 SDS) reported lower scores on emotional (-8.0) and cognitive functioning (-9.2) and on the cancer summary scale (-6.6), whereas parent-report scores were lower on social functioning (-7.5). Weight loss (>0.5 SDS) was associated with lower scores on physical functioning (-13.9 child-report and -10.7 parent-report), emotional (-7.4) and social functioning (-6.0) (child-report), pain (-11.6), and nausea (-7.8) (parent-report). Parents reported worse social functioning and more pain in children with weight gain (>0.5 SDS) compared with children with stable weight status.
CONCLUSIONS: Undernutrition and weight loss were associated with worse physical and social functioning, whereas overnutrition and weight gain affected the emotional and social domains of HRQL. Interventions that improve nutritional status may contribute to enhanced health outcomes in children with cancer.

PMID: 25752883 [PubMed – indexed for MEDLINE]

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A group approach to genetic counselling of cardiomyopathy patients: satisfaction and psychological outcomes sufficient for further implementation.






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A group approach to genetic counselling of cardiomyopathy patients: satisfaction and psychological outcomes sufficient for further implementation.
Eur J Hum Genet. 2015 Nov;23(11):1462-7
Authors: Ot… Continue reading

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Caregiving demands and caregivers’ psychological outcomes: The mediating role of perceived injustice.






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Caregiving demands and caregivers’ psychological outcomes: The mediating role of perceived injustice.
Clin Rehabil. 2016 Apr 28;
Authors: Mohammadi S, de Boer MJ, Sanderman R, Hagedoorn M
Abst… Continue reading

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